Postfix is one of the most serious alternatives to Sendmail, along with Qmail and Exim. Because it is much more recent, it was built from the ground up to be as secure as possible. Postfix supports features such as ESMTP, ETRN (eg. two-way SMTP connections), LMTP (uses the LHLO command and expects to receive an ACK to check that the message is correctly delivered to each recipient), UUCP (to deliver mail between two servers with no access to the Net), AUTH to authenticate MATs at both ends (Cyrus-SASL supports AUTH), etc. The disadvantage is that you usually have to use the mail-address given to you by your provider. Most providers do not allow relaying mail using a self-made sender-address for spam-protect reasons.